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ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: Humana Press Inc., United States, Totowa, NJ] Softcover Intracellular checkpoint controls constitute a network of signal transd- tion pathways that protect cells from external stresses and internal errors. Ext- nal stresses can be generated by the continuous assault of DNA-damaging agents, such as environmental mutagens, ultraviolet (UV) light, ionizing radiation, or the reactive oxygen species that can arise during normal cellular metabolism. In response to any of these assaults on the integrity of the genome, the activation of the network of checkpoint control pathways can lead to diverse cellular responses, such as cell cycle arrest, DNA repair, or elimination of the cell by cell death (apoptosis) if the damage cannot be repaired. Moreover, internal errors can occur during the highly orchestrated replication of the cellular genome and its distribution into daughter cells. Here, the temporal order of these cell cycle events must be strictly enforcedfor example, to ensure that DNA replication is c- plete and occurs only once before cell division, or to monitor mitotic spindle assembly, and to prevent exit from mitosis until chromosome segregation has been completed. Thus, well functioning checkpoint mechanisms are central to the maintenance of genomic integrity and the basic viability of cells and, the- fore, are essential for proper development and survival. The importance of proper functioning of checkpoints be ...
ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: Humana Press Inc., United States, Totowa, NJ] Softcover Intracellular checkpoint controls constitute a network of signal transd- tion pathways that protect cells from external stresses and internal errors. Ext- nal stresses can be generated by the continuous assault of DNA-damaging agents, such as environmental mutagens, ultraviolet (UV) light, ionizing radiation, or the reactive oxygen species that can arise during normal cellular metabolism. In response to any of these assaults on the integrity of the genome, the activation of the network of checkpoint control pathways can lead to diverse cellular responses, such as cell cycle arrest, DNA repair, or elimination of the cell by cell death (apoptosis) if the damage cannot be repaired. Moreover, internal errors can occur during the highly orchestrated replication of the cellular genome and its distribution into daughter cells. Here, the temporal order of these cell cycle events must be strictly enforcedfor example, to ensure that DNA replication is c- plete and occurs only once before cell division, or to monitor mitotic spindle assembly, and to prevent exit from mitosis until chromosome segregation has been completed. Thus, well functioning checkpoint mechanisms are central to the maintenance of genomic integrity and the basic viability of cells and, the- fore, are essential for proper development and survival. The importance of proper functioning of checkpoints be ...
ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: Humana] Hardcover Ex- library book with stamps/ stickers [Simi Valley, CA, U.S.A.] [Publication Year: 2004]
ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: Humana] Hardcover Ex- library book with stamps/ stickers [Simi Valley, CA, U.S.A.] [Publication Year: 2004]
Humana, 6/24/2004 12:00:01 A. hardcover. Good. 0.9016 9.2008 6.0000. Ex- library book with stamps/ stickers\r\n Date: 2000. Humana ISBN 1588295001 9781588295002 [US]
ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: Humana Press] Hardcover pp. 380 52:B&W 6.14 x 9.21in or 234 x 156mm (Royal 8vo) Case Laminate on White w/Gloss Lam [Hounslow, United Kingdom] [Publication Year: 2004]
ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: Humana] Hardcover New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service. [Irving, TX, U.S.A.] [Publication Year: 2004]
ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: Humana] Hardcover New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service. [Irving, TX, U.S.A.] [Publication Year: 2004]
ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: Humana] Hardcover Book is in Used-Good condition. Pages and cover are clean and intact. Used items may not include supplementary materials such as CDs or access codes. May show signs of minor shelf wear and contain limited notes and highlighting. [Hawthorne, CA, U.S.A.] [Publication Year: 2004]
ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: HUMANA PRESS] Hardcover Ship within 24hrs. Satisfaction 100% guaranteed. I Ships from multiple Locations I "Special Note" We do not Provide Service On APO & PO BOX Box addresses. Delivery with In 7-14 working Day Only. This Books ship from the United Kingdom & USA other locations in India depending on your location and availability. [London, LONDO, United Kingdom] [Publication Year: 2004]
ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: Humana] Hardcover New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service. [Irving, TX, U.S.A.] [Publication Year: 2004]
ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: Humana] Hardcover New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service. [Irving, TX, U.S.A.] [Publication Year: 2004]
ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: Humana Press] Hardcover Intracellular checkpoint controls constitute a network of signal transd- tion pathways that protect cells from external stresses and internal errors. Ext- nal stresses can be generated by the continuous assault of DNA-damaging agents, such as environmental . [Greven, Germany] [Publication Year: 2004]
Hard Cover. New. New Book; Fast Shipping from UK; Not signed; Not First Edition; The Checkpoint Controls and Cancer : Volume 2: Activation and Regulation Protocols. ISBN 1588295001 9781588295002 [GB]
ISBN10: 1588295001, ISBN13: 9781588295002, [publisher: Humana Press] Hardcover Intracellular checkpoint controls constitute a network of signal transd- tion pathways that protect cells from external stresses and internal errors. Ext- nal stresses can be generated by the continuous assault of DNA-damaging agents, such as environmental . [Greven, Germany] [Publication Year: 2004]
SR-ECOMMERCE. New. SR-ECOMMERCE ISBN 1588295001 9781588295002 [IN]
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When you click on links to various merchants on this site and make a purchase, this can result in this site earning a commission at no extra cost to you. Affiliate programs and affiliations include, but are not limited to, the eBay Partner Network, Amazon and Alibris.
