Springer, Date: 2003. *Price HAS BEEN REDUCED by 10% until Monday, April 29 (sale item)* 296 pp., Hardcover, ex library, text clean & binding tight. - If you are reading this, this item is actually (physically) in our stock and ready for shipment once ordered. We are not bookjackers. Buyer is responsible for any additional duties, taxes, or fees required by recipient's country. 2003. Springer ISBN 3540442081 9783540442080 [US]

Secaucus, New Jersey: Springer Verlag, Date: 2003. Hard Cover. Very Good/No Dust Jacket. Very good copy with minor shelfwear. 2003. Springer Verlag ISBN 3540442081 9783540442080 [US]

Springer Verlag 2003 2003 ed. Hard Cover Very Good. No Dust Jacket Very good copy with minor shelfwear.

ISBN10: 3540442081, ISBN13: 9783540442080, [publisher: Berlin Heidelberg Springer Verlag] Hardcover Gebraucht - Gut Zustand: Gut, Mängelexemplar, XII, 296 p. 38 illus., 6 in color. About this book: Chromatin dynamics is a consequence of protein complexes that modify histones, remove histone modifications, mobilize nucleosomes or stabilize nucleosomes. A wide variety of such complexes have now been described. Some are abundant and may play global roles, others are more rare and specialized for functions at discreet loci. Several complexes share biochemical activities and genetic studies suggest overlapping functions. Many components of these complexes were first revealed in genetic screens, while others were discovered by novel biochemical approaches. This volume of Current Topics in Microbiology and Immunology reviews a wide variety of protein complexes that modify chromatin. Written for researchers and scientists in the field of human genetics. Englisch
[Darmstadt, Germany] [Publication Year: 2003]

ISBN10: 3540442081, ISBN13: 9783540442080, [publisher: Springer] Hardcover 296 pages. A Good clean copy.This book provides timely reviews of several protein complexes that regulate gene expression and chromatin dynamics. Examples of such complexes include: nucleosome assembly complexes, ATPdependent chromatin remodeling complexes, histone acetyltransferase complexes, histone deacetylase complexes, heterochromatin complexes, SMC complexes and transcription elongation complexes. These chapters will bring experts in the field up to date on several aspects of chromosome biology and will provide an exiting introduction to the field for new chromatin researchers. An early view of eukaryotic chromosomes was that of static structures, which stored DNA not in use within a given cell type. It was thought that packaging of DNA into higher levels of chromatin structure would suffice to repress gene expression and that the challenge to the cell would be to rescue specific sequences from these structures. The extensive packaging of inactive DNA was considered the primary difference between eukaryotic and prokaryotic genomes and except for that point both would be similarly regulated by cisacting sequences and trans acting factors. Our view of eukaryotic chromosomes has evolved dra matically over the last decade. The picture of chromosomes that is emerging is that of dynamic breathing organelles actively regulating the flow of genetic information from the genome. Indeed chromatin is ...

ISBN10: 3540442081, ISBN13: 9783540442080, [publisher: Springer Berlin Heidelberg] Hardcover Druck auf Anfrage Neuware - Printed after ordering - An early view of eukaryotic chromosomes was that of static structures, which stored DNA not in use within a given cell type. It was thought that packaging of DNA into higher levels of chromatin structure would suffice to repress gene expression and that the challenge to the cell would be to rescue specific sequences from these structures. The exten sive packaging of inactive DNA was considered the primary difference between eukaryotic and prokaryotic genomes and except for that point both would be similarly regulated by cis-acting sequences and trans acting factors. Our view of eukaryotic chromosomes has evolved dra matically over the last decade. The picture of chromosomes that is emerging is that of dynamic breathing organelles actively regulating the flow of genetic information from the genome. Indeed chromatin is so fluid that even maintaining gene quiescence is an active process and is tightly regulated. Chromatin dynamics is a consequence of protein complexes that modify histones, remove histone modifications, mobi lize nucleosomes or stabilize nucleosomes. Awide variety of such com plexes have now been described. Some are abundant and may play glo bal roles in chromosome fluidity and function. Others are more rare and specialized for specific functions at discreet loci. Moreover, several complexes share biochemical ac ...
Show/Hide image

ISBN10: 3540442081, ISBN13: 9783540442080, [publisher: Springer Berlin Heidelberg] Hardcover Druck auf Anfrage Neuware - Printed after ordering - An early view of eukaryotic chromosomes was that of static structures, which stored DNA not in use within a given cell type. It was thought that packaging of DNA into higher levels of chromatin structure would suffice to repress gene expression and that the challenge to the cell would be to rescue specific sequences from these structures. The exten sive packaging of inactive DNA was considered the primary difference between eukaryotic and prokaryotic genomes and except for that point both would be similarly regulated by cis-acting sequences and trans acting factors. Our view of eukaryotic chromosomes has evolved dra matically over the last decade. The picture of chromosomes that is emerging is that of dynamic breathing organelles actively regulating the flow of genetic information from the genome. Indeed chromatin is so fluid that even maintaining gene quiescence is an active process and is tightly regulated. Chromatin dynamics is a consequence of protein complexes that modify histones, remove histone modifications, mobi lize nucleosomes or stabilize nucleosomes. Awide variety of such com plexes have now been described. Some are abundant and may play glo bal roles in chromosome fluidity and function. Others are more rare and specialized for specific functions at discreet loci. Moreover, several complexes share biochemical ac ...
Show/Hide image

Very Good. ISBN 3540442081 9783540442080 [US]