ISBN10: 0128122617, ISBN13: 9780128122617, [publisher: Elsevier Science & Technology, Academic Press] Hardcover nach der Bestellung gedruckt Neuware - Printed after ordering - Sirtuins in Health and Disease, Volume 154 presents the reactions catalyzed by sirtuins in terms of their unique coenzyme NAD+-dependent catalytic mechanisms, the ways to elucidate these mechanisms, and the design of the inhibitory compounds against the sirtuin-catalyzed reactions as potential therapeutic agents for human diseases. Sections cover the concepts and chemical tools in sirtuin research, SIRT4 and SIRT7, the regulatory effects of NAD metabolic pathways on sirtuin activity, sirtuins as modifiers of Huntington's Disease (HD) pathology, parasite sirtuins as targets for novel chemotherapeutic agents, targeting sirtuins - substrate specificity and inhibitor design, and chemical probes in sirtuin research. This book focuses on the outstanding issues in the sirtuin field and implications for future sirtuin research.
[Einbeck, Germany] [Publication Year: 2018]
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Elsevier Science 1/27/2018 12: 00: 00 AM Hardcover New Book. Shipped from US in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the US.

ISBN10: 0128122617, ISBN13: 9780128122617, [publisher: Academic Pr] Hardcover 175 pages. 9.00x6.00x0.50 inches. In Stock.
[Exeter, United Kingdom] [Publication Year: 2018]

Academic Pr 2018 Hardcover New 175 pages. 9.00x6.00x0.50 inches.