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Never tell a young person that anything cannot be done. God may have been waiting centuries for someone ignorant enough of the impossible to do that very thing.
New York, NY Springer 2009 2009 ed. Hard cover New. Glued binding. Paper over boards. 199 p. Contains: Unspecified, Tables, black & white, Figures. Advances in Experimental Medicine and Biology, 650.
ISBN10: 1441902953, ISBN13: 9781441902955, [publisher: Springer Nature Singapore] Druck auf Anfrage Neuware - Printed after ordering - v(D)J recombination: for the community of immunologists and developmental biologists, the molecular route by which B and T lymphocytes acquire their unique function of affording adaptive immunity. Yet, for many-from experienced scientists to trainees-it represents a (rather too) sophisticated process whose true insight is excessively demanding. However, when not simplyconsidered as a private ground for a few aficionados, it can be seen as a way of understanding how maturelympho cytes carry on their basic functions. For the group of aficionados-which includes this editor-it is an elegant paradigm featuring many fascinating evolutionary achievements of which the biological world alone has the secret. These include a subtle biochemical principle most likelyhijacked some 470 million years ago from an ancestral gene invader and since then cleverly adapted by jawed vertebrates to precisely cleave and rearrange their antigen receptor (Ig andTCR)loci. This invader would itself have assigned the services of the nonhomologous end joining (NHEJ) DNArepair machinery as well as various DNApolymerases or transferases to work in concert with developmental clues in lymphoid cell lineages to generate an immune repertoire and efficient host surveillance while avoiding autoimmunity. Recently, important new refinements in these systems have emerged, contin ...
ISBN10: 1441902953, ISBN13: 9781441902955, [publisher: Springer Nature Singapore] Druck auf Anfrage Neuware - Printed after ordering - v(D)J recombination: for the community of immunologists and developmental biologists, the molecular route by which B and T lymphocytes acquire their unique function of affording adaptive immunity. Yet, for many-from experienced scientists to trainees-it represents a (rather too) sophisticated process whose true insight is excessively demanding. However, when not simplyconsidered as a private ground for a few aficionados, it can be seen as a way of understanding how maturelympho cytes carry on their basic functions. For the group of aficionados-which includes this editor-it is an elegant paradigm featuring many fascinating evolutionary achievements of which the biological world alone has the secret. These include a subtle biochemical principle most likelyhijacked some 470 million years ago from an ancestral gene invader and since then cleverly adapted by jawed vertebrates to precisely cleave and rearrange their antigen receptor (Ig andTCR)loci. This invader would itself have assigned the services of the nonhomologous end joining (NHEJ) DNArepair machinery as well as various DNApolymerases or transferases to work in concert with developmental clues in lymphoid cell lineages to generate an immune repertoire and efficient host surveillance while avoiding autoimmunity. Recently, important new refinements in these systems have emerged, contin ...
New York, NY Springer 2009 2009 ed. Hard cover New. Glued binding. Paper over boards. 199 p. Contains: Unspecified, Tables, black & white, Figures. Advances in Experimental Medicine and Biology, 650.
ISBN10: 1441902953, ISBN13: 9781441902955, [publisher: Springer] Hardcover Suitable for the community of immunologists and developmental biologists, this title describes the molecular route by which B and T lymphocytes acquire their unique function of affording adaptive immunity. It also describes a way of understanding how mature lymphocytes carry on their basic functions. Editor(s): Ferrier, Pierre. Series: Advances in Experimental Medicine and Biology. Num Pages: 199 pages, 5 black & white tables, biography. BIC Classification: MBGR; MJCM. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 15. Weight in Grams: 522. . 2009. 2009th Edition. hardcover. . . . . [Galway, GY, Ireland] [Publication Year: 2009]
ISBN10: 1441902953, ISBN13: 9781441902955, [publisher: Springer] Hardcover Suitable for the community of immunologists and developmental biologists, this title describes the molecular route by which B and T lymphocytes acquire their unique function of affording adaptive immunity. It also describes a way of understanding how mature lymphocytes carry on their basic functions. Editor(s): Ferrier, Pierre. Series: Advances in Experimental Medicine and Biology. Num Pages: 199 pages, 5 black & white tables, biography. BIC Classification: MBGR; MJCM. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 15. Weight in Grams: 522. . 2009. 2009th Edition. hardcover. . . . . Books ship from the US and Ireland. [Olney, MD, U.S.A.]
DISCLOSURE:
When you click on links to various merchants on this site and make a purchase, this can result in this site earning a commission at no extra cost to you. Affiliate programs and affiliations include, but are not limited to, the eBay Partner Network, Amazon and Alibris.
