ISBN10: 0124201946, ISBN13: 9780124201941, [publisher: Academic Press 2015-10-13] Hardcover
[Wallingford, United Kingdom] [Publication Year: 2015]

Elsevier Science 10/20/2015 12: 00: 00 AM Hardcover New Book. Shipped from US in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the US.

Academic Pr, Date: 2015. Hardcover. New. 1st edition. 552 pages. 9.00x6.25x1.25 inches. 2015. Academic Pr ISBN 0124201946 9780124201941 [GB]

Hardback. New. DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also discussed as a plasma and serum test for non-invasive screening, diagnostic and prognostic tests, as compared to biopsy-driven gene expression analysis, factors which have led to the use of DNA methylation as a potential tool for determining cancer risk, and diagnosis between benign and malignant disease. Therapies are at the heart of this volume and the possibilities of DNA demethylation. In cancer, unlike genetic mutations, DNA methylation and histone modifications are reversible and thus have shown great potential in the race for effective treatments. In addition, the authors present the importance of high-throughput methylome analysis, not only in cancer, but also in non-neoplastic diseases such as rheumatoid arthritis. ISBN 0124201946 9780124201941 [GB]

ISBN10: 0124201946, ISBN13: 9780124201941, [publisher: Elsevier Health Sciences] Hardcover nach der Bestellung gedruckt Neuware - Printed after ordering - DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also discussed as a plasma and serum test for non-invasive screening, diagnostic and prognostic tests, as compared to biopsy-driven gene expression analysis, factors which have led to the use of DNA methylation as a potential tool for determining cancer risk, and diagnosis between benign and malignant disease. Therapies are at the heart of this volume and the possibilities of DNA demethylation. In cancer, unlike genetic mutations, DNA methylation and histone modifications are reversible and thus have shown great potential in the race for effective treatments. In addition, the authors present the importance of high-throughput methylome analysis, not only in cancer, but also in non-neoplastic diseases such as rheumatoid arthritis.
[Einbeck, Germany] [Publication Year: ...
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Academic Pr 2015 Hardcover New 1st edition. 552 pages. 9.00x6.25x1.25 inches.

ISBN10: 0124201946, ISBN13: 9780124201941, [publisher: Academic Press] Hardcover New
[liverpool, United Kingdom] [Publication Year: 2015]